Danny Trejo
Machete Cortez
Amber Heard
Blanca Vasquez / Miss San Antonio
Charlie Sheen
Mr. President
Jessica Alba
Sartana Rivera
Vanessa Hudgens
Cereza Desdemona
Tom Savini
Osiris Amanpour
Cuba Gooding Jr.
El Camaleon
Antonio Banderas
El Camaleon
Walton Goggins
El Camaleon
William Sadler
Sheriff Doakes
Electra Avellan
Nurse Mona
Callie Hernandez
Space Babe
Alejandro Antonio
Boss of Mendez
Crystal Martinez
Wife of Mendez
Corey Burton
Trailer Voice Guy (voice)
Jason Christopher
Lieutenant Brass
J.J. Perry
Voz's Henchman (uncredited)
Alexander Rodnyansky
Radio Guest (uncredited)
Vincent Fuentes
Cabrito Cook
Jorge A. Jimenez
Dying Cartel Guy
Cheech Marin
Padre (archive footage) (uncredited)
