Peter Weller
Buckaroo Banzai
John Lithgow
Lord John Whorfin
Christopher Lloyd
John Bigboote
Robert Ito
Professor Hikita
Ronald Lacey
President Widmark
Matt Clark
Secretary of Defense
William Traylor
General Catburd
Vincent Schiavelli
John O'Connor
Mariclare Costello
Senator Cunningham
Bill Henderson
Casper Lindley
Damon Hines
Scooter Lindley
Billy Vera
Pinky Carruthers
Laura Harrington
Mrs. Johnson
Michael Santoro
Billy Travers
Jonathan Banks
Lizardo Hospital Guard
Kent Perkins
Mission Control
John Ashton
Highway Patrolman
Ken Magee
Duck Hunter Burt
James Keane
Duck Hunter Bubba
Yakov Smirnoff
National Security Advisor
Leonard Gaines
Artie Duncan
Francine Lembi
TV Anchorwoman
John Walter Davis
Star Surgeon