Michael Angarano
Will Stronghold
Mary Elizabeth Winstead
Gwen Grayson / Royal Pain
Kurt Russell
Steve Stronghold / The Commander
Kelly Preston
Josie Stronghold / Jetstream
Danielle Panabaker
Layla Williams
Bruce Campbell
Coach Boomer
Lynda Carter
Principal Powers
Kevin Heffernan
Ron Wilson, Bus Driver
Nicholas Braun
Zachary "Zach" Braun / Zack Attack
Steven Strait
Warren Peace
Khadijah Haqq McCray
Penny
Dustin Ingram
Carbon Copy Kid
Christopher Wynne
News Anchor
Cloris Leachman
Nurse Spex
Jim Rash
Mr. Grayson / Stitches
Kevin McDonald
Mr. Medulla
Zachry Rogers
Young Commander
Jill Talley
Mrs. Timmerman
Patrick Warburton
Royal Pain (voice)
Vakisha Coleman
Student Sidekick (uncredited)
Sean Gordon
Penny's Date (uncredited)
Hans Hernke
Laser-Vision Boy (uncredited)
Jason Maxim
Funky Prom Boy (uncredited)