Frank Welker
Scooby-Doo / Fred Jones (voice)
Casey Kasem
Shaggy Rogers (voice)
Mindy Cohn
Velma Dinkley (voice)
Grey DeLisle
Daphne Blake (voice)
Ron Perlman
Captain Skunkbeard / Biff Wellington (voice)
Freddy Rodríguez
Rupert Garcia (voice)
Tim Conway
Skip Jones (voice)
Edie McClurg
Peggy Jones / Sea Salt Sally (voice)
Kathy Najimy
Sunny St. Cloud (voice)
Arsenio Hall
Captain Crothers (voice)
Dan Castellaneta
Mr. Mysterio / Woodenleg Wally (voice)