Matthew McConaughey
Ron Woodroof
Michael O'Neill
Richard Barkley
Dallas Roberts
David Wayne
Donna DuPlantier
Nurse Frazin
Ian Casselberry
Hispanic Orderly
James DuMont
Rayon's Father
Jane McNeill
Francine Suskind
Matthew Thompson
Effeminate Man
Jonathan Tabler
Rick Ferris
Carl Palmer
FDA Customs Agent
Craig Borten
Quicksilver Cowboy
Arthur Smith
Rodeo Announcer
Adam Dunn
Neddie Jay (uncredited)
Juliet Reeves London
Rodeo Girl (uncredited)
Jeanine Hill
Rodeo Girl (uncredited)
Sarah Eilts
Ron's Hooker (uncredited)
Lily Virginia Filson
Dancer (uncredited)
Steffie Grote
The Girl With The Snake Tattoo (uncredited)