Owen Wilson
Reggie (voice)
Woody Harrelson
Jake (voice)
George Takei
S.T.E.V.E. (voice)
Colm Meaney
Myles Standish (voice)
Keith David
Chief Broadbeak (Voice)
Dan Fogler
Governor William Bradford (voice)
Jimmy Hayward
Ranger / Leatherbeak / President / Hazmats (voice)
Jeff Biancalana
General Sagan / Hazmats (voice)
Carlos Ponce
Narrator / Alejandro (voice)
Robert Beltran
Chief Massasoit (voice)
Lesley Nicol
Female Pilgrim (voice)
Kaitlyn Maher
President's Daughter (voice)
Carlos Alazraqui
Amos (voice)
Jason Finazzo
Chrononaut One (voice)
Scott Mosier
Pizza Dude (voice)
Lauren Bowles
Jake's Mother (voice)
Dwight Howard
Cold Turkey (Voice)
William Morgan Sheppard
(voice)
