Kamal Haasan
Govindarajan Ramaswamy / Rangaraja Nambi / George W. Bush / Avtaar Singh / Balram Naidu / Christian Fletcher / Shinghen Narahasi / Krishnaveni / Vincent Poovaragavan / Kalifullah Mukhtaar
Asin Thottumkal
Kodhai Radha / Andal
Napoleon
Kulothunga Chola II
P. Vasu
J. Ragavendra (Jaa Raa)
Shammu
Assistant Biotechnologist
M. S. Bhaskar
Broadway Kumar
Santhana Bharathi
J. Ragavendra's brother-in-law
R. Sundarrajan
Member of Legislative Assembly
David W. Scott
Lab Tech / Detective
Brian Jennings
Chief of Home Land Security
Rekha
Meenakshi Ragavendra