Susan Sarandon
Michaela Odone
Peter Ustinov
Professor Nikolais
Ann Hearn
Loretta Muscatine
Aaron Jackson
Francesco Odone
Laura Linney
Young Teacher
Kathleen Wilhoite
Deirdre Murphy
Gerry Bamman
Doctor Judalon
Margo Martindale
Wendy Gimble
James Rebhorn
Ellard Muscatine
LaTanya Richardson Jackson
Nurse Ruth
Jennifer Dundas
Nurse Nancy Jo
Becky Ann Baker
Pellerman's Secretary
Mary Pat Gleason
The Librarian
Peter MacKenzie
Immunosuppression Doctor
Paul Lazar
Professor Duncan
Michael O'Neill
School Psychologist
Richard Cordery
Suddaby's Senior Manager
Angus Barnett
Suddaby's Junior Manager
Elizabeth Daily
Lorenzo Odone (voice)
Zack O'Malley Greenburg
Lorenzo Odone
Amelia Campbell
Murphy Family
Keith Reddin
Murphy Family
Anthony Dileo Jr.
Conference Parent
Lianne Kressin
Smiling Nurse