John Hurt
Dr. Joe Buchanan / Narrator (voice)
Raúl Juliá
Dr. Victor Frankenstein
Bridget Fonda
Mary Wollstonecraft Godwin
Jason Patric
Lord George Gordon Byron
Michael Hutchence
Percy Byshee Shelley
Catherine Rabett
Elizabeth Lavenza
Catherine Corman
Justine Moritz
William Geiger
Lab Technician
Myriam Cyr
Information Officer
Terri Treas
Buchanan's Car (voice)
Isabella Rocchietta
Dorrie