Robert De Niro
David 'Noodles' Aaronson
James Woods
Maximilian 'Max' Bercovicz
Elizabeth McGovern
Deborah Gelly
Treat Williams
James Conway O'Donnell
James Hayden
Patrick 'Patsy' Goldberg
William Forsythe
Philip 'Cockeye' Stein
Larry Rapp
'Fat' Moe Gelly
Scott Schutzman Tiler
Young Noodles
Rusty Jacobs
Young Max / David Bailey
Jennifer Connelly
Young Deborah
Adrian Curran
Young Cockeye
Mike Monetti
Young 'Fat' Moe Gelly
Danny Aiello
Police Chief Vincent Aiello
Richard Bright
Chicken Joe
Richard Foronjy
Officer Whitey
Olga Karlatos
Woman in the Puppet Theatre
Jerry Strivelli
Johnny Capuano
Sandra Solberg
Friend of Young Deborah
Margherita Pace
Young Deborah (Double)
Bruno Bilotta
Chinese Theater Spectator (uncredited)
Angelo Florio
Willie the Ape
Marcia Jean Kurtz
Max's Mother
Frankie Caserta
Bugsy's Gang
Joey Marzella
Bugsy's Gang
Ann Neville
Girl in Coffin
Joey Faye
Adorable Old Man
Linda Ipanema
Nurse Thompson
Marty Licata
Cemetery Caretaker
Estelle Harris
Peggy's Mother
Alexander Godfrey
Newstand Man
Cliff Cudney
Mounted Policeman
Paul Farentino
2nd Mounted Policeman
Bruce Bahrenburg
Sgt. P. Halloran
Mort Freeman
Street Singer
Salvatore Billa
One of Beefy's Thugs (uncredited)
Scott Coffey
Bugsy's Gang (uncredited)
Marco Stefanelli
Bugsy's Gang (uncredited)
Matteo Cafiso
Boy in Park (uncredited)
Nunzio Giuliani
Speakeasy Drum Player (uncredited)
Nelson Camp
Newspaper Salesman (uncredited)
Dario Iori
Speakeasy Banjo Player (uncredited)
Ole Jorgensen
Speakeasy Percussionist (uncredited)
Francesca Leone
David Bailey's Girlfriend (uncredited)
Chuck Low
Deborah Gelly's Father (uncredited)
Ron Nummi
Waiter (uncredited)
Ryan Paris
Speakeasy Patron (uncredited)
Nicola Roberto
Speakeasy Trumpet Player (uncredited)
Gianni Sanjust
Speakeasy Clarinet Player (uncredited)
Alex Serra
Speakeasy Vocalist (uncredited)
Susan Spafford
Nurse (uncredited)
Mark Frazer
Pimp (uncredited)
Maria Pia Monicelli
Prostitute (uncredited)
Claudio Mancini
Syndacalist (uncredited)
Rossana Canghiari
Speakeasy Patron (uncredited)