Tom Holland
Peter Parker / Spider-Man
Michael Keaton
Adrian Toomes / Vulture
Robert Downey Jr.
Tony Stark / Iron Man
Gwyneth Paltrow
Pepper Potts
Bokeem Woodbine
Herman Schultz / Shocker #2
Hannibal Buress
Coach Wilson
Kenneth Choi
Principal Morita
Martin Starr
Mr. Harrington
Garcelle Beauvais
Doris Toomes
Michael Chernus
Phineas Mason / Tinkerer
Logan Marshall-Green
Jackson Brice / Shocker #1
Jennifer Connelly
Karen / Suit Lady (voice)
Tunde Adebimpe
Mr. Cobbwell
Kirk R. Thatcher
Punk on Street
Sondra James
Yelling Woman
Gary Richardson
Day Sleeper
Wayne Pére
History Teacher
Chris Evans
Steve Rogers / Captain America
Kerry Condon
Friday (voice)
Amy Hill
Decathlon Moderator
Miles Mussenden
Park Ranger
Kevin LaRosa Jr.
Helicopter Pilot
Ari Groover
Ferry Commuter
Louis Gonzalez
Ferry Commuter
Stewart Steinberg
Ferry Commuter
Andy Powers
Ferry Commuter
Omar Capra
Yeah Spider-Man Guy
Vince Foster
Stark Tower Technician
Brian Schaeffer
Stark Tower Employee
Chris Adams
NYC Pedestrian (uncredited)
Maiya Boyd
Indian Flower Girl (uncredited)
Rebeca Donovan
Drama Club Member (uncredited)
Elli
Rabbi on Subway (uncredited)
Nickolas Wolf
Mascot (uncredited)
Jaine Ye
Chemistry Student (uncredited)
Gina Cordan
DC Tourist (uncredited)
Friday Chamberlain
Skateboarder (uncredited)
Dante Brattelli
Homecoming Dance Student (uncredited)
Melissa Kay Glaze
New Yorker (uncredited)
Donald K. Overstreet
Avenger's Staff Agent (uncredited)
Hallie Ricardo
DC News Reporter (uncredited)
Doug Scroggins III
Stark VTOL Pilot (uncredited)
Marmee Regine Cosico
NY Pedestrian (uncredited)
Harrison Osterfield
Midtown High Student (uncredited)
Chris Silcox
Helicopter D.C. Metro Sniper (uncredited)
Clam Sepulveda
Ned Leed's Dad (uncredited)
Wesley Kuykendoll
Vulture Weapons Tech (uncredited)
Cassidy Alexandra Kahler
Flash's Prom Date (uncredited)