Boris Karloff
Dr. Fu Manchu
Karen Morley
Sheila Barton
Charles Starrett
Terence Granville
Lawrence Grant
Sir Lionel Barton
C. Montague Shaw
Curator Dr. Fairgyle - British Museum Official (uncredited)
Steve Clemente
Knife Thrower (uncredited)
Allen Jung
Coolie (uncredited)
Chris-Pin Martin
Potentate (uncredited)
Edward Peil Sr.
Coolie Spy (uncredited)
Willie Fung
Ship's Steward (uncredited)
E. Alyn Warren
Goy Lo Sung - Fu Manchu Messenger (uncredited)
Olive Young
Cantina singer (uncredited)
Everett Brown
Slave (uncredited)
Clinton Rosemond
Slave (uncredited)