Tony Shalhoub
Misha Vilyenkov
Bruce Davison
Dr. Reingold
Trini Alvarado
Adult Marie Alweather
Jay Mohr
Benny / Paulie (voice)
Hallie Eisenberg
Marie Alweather
Matt Craven
Warren Alweather
Bill Cobbs
Virgil the Janitor
Tia Texada
Ruby / Lupe (voice)
Laura Harrington
Lila Alweather
Peter Basch
Graduate Student #1
Emily Mura-Smith
Graduate Student #2
Tamara Zook
Speech Therapist
Nicole Chamberlain
Shirley
Dig Wayne
Research Assistant #1
Michael Leydon Campbell
Research Assistant #2
Kristie Transeau
Veterinarian
Francesca Federico-O'Murchu
Molly