Neil Patrick Harris
Patrick Winslow
Jonathan Winters
Papa Smurf (voice)
Katy Perry
Smurfette (voice)
Anton Yelchin
Clumsy Smurf (voice)
Sofía Vergara
Odile Anjelou
Frank Welker
Azrael (voice)
Mark Doherty
Bluetooth Businessman
Sean Kenin
Guy in Plaid Shirt
Adria Baratta
Anjelou Employee
Paula Pizzi
Odile's Mother
Julianna Rigoglioso
Little Sister
Daria Rae Figlo
Blonde Sister
Bradley Gosnell
Toy Salesperson
Heidi Armbruster
Toy Store Parent
Finnerty Steeves
Toy Store Parent
John Speredakos
Parent with Girls
Eric Redgate
Skateboard Kid
Jojo Gonzalez
FAO Custodian
Sean Ringgold
Inmate Bubba
Mario D'Leon
Bubba's Inmate Friend
Olivia Palermo
Party Guest
Lauren Waggoner
Party Guest
Alan Cumming
Gutsy Smurf (voice)
Fred Armisen
Brainy Smurf (voice)
George Lopez
Grouchy Smurf (voice)
Kenan Thompson
Greedy Smurf (voice)
Jeff Foxworthy
Handy Smurf (voice)
John Oliver
Vanity Smurf (voice)
Wolfgang Puck
Chef Smurf (voice)
Gary Basaraba
Hefty Smurf (voice)
Paul Reubens
Jokey Smurf (voice)
B.J. Novak
Baker Smurf (voice)
Tom Kane
Narrator Smurf (voice)
John Kassir
Crazy Smurf (Voice)
Joel McCrary
Farmer Smurf (voice)
Mary McGloin
Mother of Girl in Store (uncredited)