Antonio Banderas
Puss in Boots (voice)
Salma Hayek Pinault
Kitty Softpaws (voice)
Zach Galifianakis
Humpty Dumpty (voice)
Billy Bob Thornton
Jack (voice)
Constance Marie
Imelda (voice)
Mike Mitchell
Andy Beanstalk (voice)
Rich Dietl
Bounty Hunter (voice)
Guillermo del Toro
Comandante / Hombre del bigote (voice)
Conrad Vernon
Raoul / Soldier (voice)
Chris Miller
Little Boy Blue / Friar Miller / Prison Guard / Manuel / Rafael (voice)
Tom Wheeler
Bartender / Mean Boy / Wagon Driver / Hotel Owner / Rodrigo (voice)
Tom McGrath
Bar Thief (voice)
Bob Joles
Giuseppe (voice)
Latifa Ouaou
Crazy Woman / Mean Girl / Milk Lady / Little Boy (voice)
Jessica Schulte
Estella Maria (voice)
Bob Persichetti
Ohhh Cat (voice)
Nina Barry
Ivana / Charo (voice)
Sergio Bruna
Soldier (voice) (uncredited)
Roberto Donati
Various (voice) (uncredited)
Rebecca Davis
Various Cats (voice) (uncredited)
Joshua Rush
Additional Voices (voice) (uncredited)
Lara Jill Miller
Additional Voices (voice) (uncredited)
Jossara Jinaro
Additional Voices (voice) (uncredited)
Julie Wittner
Various Cats (voice) (uncredited)