Renée Elise Goldsberry
Henrietta Lacks
Oprah Winfrey
Deborah Lacks
Ninja N. Devoe
Country Girl Mae
Patrick Walker
Cousin Fred
Sylvia Grace Crim
Mary Kubicek
Tian Richards
Lawrence (16 yrs.)
Jock McKissic
Carl the Mechanic
Kyanna Simone Simpson
Deborah (15-24YRS)
Kayla Anderson
Johns Hopkins Student
Karen Wheeling Reynolds
Mrs. Gey
Jordan Eli Arellano
Young Sonny Lacks
Tatom Pender
Johns Hopkins Nurse
Christopher Robert Escobar
Chris the Intern
De'Marco Arrington
Young Joe
Tashaun Stanfill-Perry
Henrietta Lacks Neighbor
Matthew Bernard
Johns Hopkins Student
Elizabeth Hackler
Rebecca's Co-worker
Raphael Dante' Carr Jr.
Young Sonny
Miguel Angel Marrero
Scientist
Courtney B. Vance
Sir Lord Keenan Coefield
Reed Birney
Dr. George Gey
Alpha Trivette
First Administrator
Terrence V. Walker
Church Patron
Gabriel Ebert
Christoph Lengauer
Kent Wagner
Scientist (uncredited)