Paul Giamatti
Barney Panofsky
Dustin Hoffman
Izzy Panofsky
Rosamund Pike
Miriam Grant-Panofsky
Minnie Driver
The 2nd Mrs. P
Rachelle Lefevre
Clara 'Chambers' Charnofsky
Mark Addy
Detective O'Hearne
Jake Hoffman
Michael Panofsky
Anna Hopkins
Kate Panofsky
Harvey Atkin
2nd Mrs. P's Father
Linda Sorensen
2nd Mrs. P's Mother
Brittany Drisdelle
Girl at Cafe
Paul Gross
Constable O'Malley of the North
Maury Chaykin
Wedding Guest
Larry Day
Bartender at Wedding
Mark Camacho
T / U Productions Executive #1
Harry Strandjofski
Dr. Morty
Atom Egoyan
O'Malley Director #1
David Cronenberg
O'Malley Director #2
Ted Kotcheff
Train Conductor
David Pryde
T / U Productions Executive #1
Paula Jean Hixson
Bartender at Grumpy's
Marica Pellegrinelli
The Countess
Domenico Minutoli
Judge at Rome Wedding
Massimo Wertmüller
Rome Doctor
Sam Stone
Fundraising Target #1
Burney Lieberman
Fundraising Target #2
Morty Bercovitch
Fundraising Target #3
Pauline Little
The 2nd Mrs. P's Housekeeper
Robin Kazdan
Wedding Guest
Sheila Hymans
Rabbi's Wife
Kyle Switzer
Production Assistant
Rebecca Croll
Receptionist #1
Steve Bienstock
NY Restaurant Waiter
Zack Kifell
Young Michael Panofsky
Simone Richler
Young Kate Panofsky
Denys Arcand
Maitre'D at Ritz
Arthur Grosser
Mr. Dalhousie
Pascale Bourbeau
Woman at Cemetery
Ellen David
Massage Parlour Madame
Marina Eva
Leo's Girlfriend
Sandra Lavoie
Barney's One Night Stand
Ivana Shein
Receptionist #2
Mélanie St-Pierre
O'Malley's New Co-Star
Richard J. Lewis
Pathologist
Howard Rosenstein
Cousin Jeff