Ryan Reynolds
Wade Wilson / Deadpool / Nicepool
Hugh Jackman
Logan / Wolverine
Emma Corrin
Cassandra Nova
Matthew Macfadyen
Mr. Paradox
Henry Cavill
The Cavillrine
Brianna Hildebrand
Negasonic Teenage Warhead
Stefan Kapičić
Colossus (voice)
Nanak Phlora
Elliot Chipman
Leemore Marrett Jr.
Minuteman Leader
Greg Hemphill
Seedy Bartender
Rob McElhenney
TVA Soldier
James Reynolds
Screaming Mutant (voice)
Paul G. Raymond
TVA Office Agent
Blake Lively
Ladypool (voice)
Inez Reynolds
Kidpool (voice)
Nathan Fillion
Headpool (voice)
Matthew McConaughey
Cowboypool (voice)
OIin Reynolds
Babypool (voice)
Alex Kyshkovych
Canadapool
Chris Hemsworth
Thor Odinson (archive footage) (uncredited)
Billy Clements
Russian (uncredited)
Daniel Medina Ramos
Toad (uncredited)
Jade Lye
Lady Deathstrike (uncredited)
Nilly Cetin
Quill (uncredited)
Eduardo Gago Muñoz
Azazel (uncredited)
Chloe Kibble
Callisto (uncredited)
Curtis Rowland Small
Bullseye (uncredited)
Ayesha Hussain
Psylocke (uncredited)
Jessica Walker
Arclight (uncredited)
Harry Holland
Haroldpool (uncredited)
Kevin Fortin
Zenpool (uncredited)