Robert Downey Jr.
Sherlock Holmes
Noomi Rapace
Madam Simza Heron
Jared Harris
Professor James Moriarty
Rachel McAdams
Irene Adler
Eddie Marsan
Inspector Lestrade
Stephen Fry
Mycroft Holmes
Paul Anderson
Colonel Sebastian Moran
Geraldine James
Mrs. Hudson
William Houston
Constable Clark
Wolf Kahler
Doctor Hoffmanstahl
Patricia Slater
Shush Club Maitre D'
Karima McAdams
Shush Club Maitre D'
Richard Cunningham
Businessman
Marcus Shakesheff
Hashisheen
Mark Sheals
Cock Fight Referee
George Taylor
University Student
Mike Grady
Train Conductor
Thorston Manderlay
Alfred Meinhard
Vladimir "Furdo" Furdik
Andrzej
Thierry Neuvic
Claude Ravache
Martin Nelson
Commendatore
Mark Llewelyn-Evans
Don Giovanni
Peter Stark
German Officer
Roman Jankovič
German Officer
Fredrick Ruth
Ballroom Attendant
Carsten Hayes
Ballroom Photographer
Jonathan Christie
Diplomat
Laurentiu Possa
Rene Heron
Clive Russell
Captain Tanner
Sala Baker
Adler's Escort (uncredited)