John Krasinski
Dad / Marshmallow (voice)
Phoebe Waller-Bridge
Blossom (voice)
Louis Gossett Jr.
Lewis (voice)
Catharine Daddario
Bea’s Mom
Audrey Hoffman
Bea (Ages 3 & 5)
Laquet Sharnell Pringle
Receptionist
Barbara Andres
Woman Upstairs
Alexander Rivero
Custodian
Shauna Pinkett
Hospital Receptionist
Sa'Raya Paris Johnson
7 Year-Old Girl
Marta Siteiya Moipei
Coffee Shop Barista
David Weissmann
Young Jeremy
Emily Blunt
Unicorn (voice)
George Clooney
Spaceman (voice)
Bradley Cooper
Ice (voice)
Richard Jenkins
Art Teacher (voice)
Keegan-Michael Key
Slime (voice)
Blake Lively
Octopuss (voice)
Sebastian Maniscalco
Magician Mouse (voice)
Christopher Meloni
Cosmo (voice)
Matthew Rhys
Ghost (voice)
Sam Rockwell
Guardian Dog (voice)
Maya Rudolph
Alligator (voice)
Amy Schumer
Gummy Bear (voice)
Allyson Seeger
Viola (voice)
Craig "Radioman" Castaldo
Radio Man (uncredited)