Robert De Niro
Jack Byrnes
Dustin Hoffman
Bernie Focker
Barbra Streisand
Rozalin Focker
Spencer Pickren
Little Jack 'L.J.' Byrnes
Bradley Pickren
Little Jack 'L.J.' Byrnes
Alanna Ubach
Isabel Villalobos
Ray Santiago
Jorge Villalobos
Tim Blake Nelson
Officer LeFlore
Kali Rocha
Flight Attendant
Dorie Barton
Airline Clerk
Jack Plotnick
Rent-a-Car Agent
Wayne Thomas Yorke
Airport Security Guard
Myra Turley
Admitting Nurse
Vahe Bejan
Gunther - Immigrant Man
Kathleen Gati
Venka - Immigrant Woman
Kyle T. McNamee
Undercover Waiter
Cedric Yarbrough
Prison Guard
Benjamin Trueblood
Newborn Baby
Bruno Coon
Strolling Minister / Band Member
Rock Deadrick
Wedding Band
Bernadette Pérez
Girl Bus Driver
Tiffany Turner
Girl on Bus
David Zimmerman
Dom Focker (uncredited)
John Carey
Party Guest (uncredited)
Angela Casassa
Girl at Wedding (uncredited)
Victoria Chalaya
Pam's Cousin (uncredited)
Alfredo Dalmano
Party Guest (uncredited)
Karen-Eileen Gordon
Anita Focker (uncredited)
Fabrizio Imas
Chicken Man (uncredited)
Angie Jaree
Bunny Focker (uncredited)
Sarah Kane
Senior Yoga Class Attendee (uncredited)
R. Martin Klein
Mo Focker (uncredited)
Allan Kolman
Harry Focker (uncredited)
Sean LoGrasso
Party Guest (uncredited)
Chris Mala
Wedding Guest (uncredited)
Rana McAnear
Party Guest (uncredited)
Connie Richmond
Frida Focker (uncredited)
Antonio Rufino
Waiter (uncredited)
Jimmy Star
Party Guest (uncredited)
Scott Stewart
Pedestrian (uncredited)