Matt Damon
Cale Tucker (voice)
Bill Pullman
Captain Korso (voice)
Drew Barrymore
Akima (voice)
John Leguizamo
Gune (voice)
Janeane Garofalo
Stith (voice)
Ron Perlman
Prof. Sam Tucker (voice)
Alex D. Linz
Young Cale (voice)
Jim Breuer
The Cook (voice)
Jim Cummings
Chowquin (voice)
Charles Rocket
Firrikash (voice)
Ken Hudson Campbell
Po (voice)
Tsai Chin
Old Woman (voice)
Crystal Scales
Drifter Girl (voice)
David L. Lander
Mayor of New Bangkok (voice)
Roger L. Jackson
First alien (voice)
Chris Scarabosio
Queen Drej (voice)
Elaine A. Clark
Citizen (voice)
Leslie Hedger
First Human (voice)
Roy Conrad
Second Human (voice)
Thomas A. Chantler
Male Announcer (voice)