Madonna
Breathless Mahoney
Glenne Headly
Tess Trueheart
Seymour Cassel
Sam Catchem
Charles Durning
Chief Brandon
Dick Van Dyke
D.A. Fletcher
Michael J. Pollard
Bug Bailey
Lawrence Steven Meyers
Little Face
Tony Epper
Steve the Tramp
Estelle Parsons
Mrs. Trueheart
Charles Fleischer
Reporter
Mary Woronov
Welfare Person
Catherine O'Hara
Texie Garcia
Michael Donovan O'Donnell
McGillicuddy
Robert Costanzo
Lips' Bodyguard
Jack Kehoe
Customer at Raid
Jack Goode Jr.
Lab Technician
Ray Stoddard
Lab Technician
Frank Campanella
Judge Harper
Sharmagne Leland-St. John
Club Ritz Patron
Bing Russell
Club Ritz Patron
Tom Finnegan
Uniform Cop at Ritz
Billy Clevenger
Newspaper Vendor
Ned Claflin
Radio Announcer
John Moschitta Jr.
Radio Announcer (voice)
Neil Ross
Radio Announcer (voice)
Walker Edmiston
Radio Announcer (voice)
Mike Mazurki
Old Man at Hotel
Tamara Carrera
Cigarette Girl (uncredited)
Bernie Jones
Night Club Musician (uncredited)
Sheila Lussier
Gangster's Girlfriend (uncredited)
Bruce Mahler
Reporter (uncredited)
Jerry St. John
Driver (uncredited)
