Taylor Momsen
Cindy Lou Who
Jeffrey Tambor
Mayor Augustus Maywho
Christine Baranski
Martha May Whovier
Molly Shannon
Betty Lou Who
Josh Ryan Evans
8-Year-Old Grinch
Bryce Dallas Howard
Surprised Who
Lacey Kohl
Christina Whoterberry
Rance Howard
Elderly Timekeeper
Jeremy Howard
Drew Lou Who
Jim Meskimen
Officer Wholihan
Deep Roy
Post Office Clerk
Ben Bookbinder
8-Year-Old Augustus Maywho
Michaela Gallo
Who Schoolgirl
Landry Allbright
8-Year-Old Martha May Whovier
Reid Kirchenbauer
8-Year-Old Whobris
Q'orianka Kilcher
Little Choir Member
Caroline Williams
Tiny Who Woman
Grainger Esch
Near Miss Who
Charles Croughwell
Balloon Who
Frank Welker
Max the Dog (voice)
Anthony Hopkins
Narrator (voice)