Bill Murray
Garfield (voice)
Stephen Tobolowsky
Happy Chapman
Mark Christopher Lawrence
Christopher Mello
Jimmy Kimmel
Spanky (voice)
Debra Messing
Arlene (voice)
Alan Cumming
Persnikitty (voice)
David Eigenberg
Nermal (voice)
Richard Kind
Dad Rat (voice)
Vanessa Campbell
Miss Ace Hardware
Alyson Stoner
Kid Rat (voice)
Rufus Gifford
Dog Owner #1
Randee Reicher
Dog Owner #2
Bill Hoag
Roy the Lodge Member
Michael Monks
Deputy Hopkins
Mel Rodriguez
Security Officer
Ryan McKasson
Dog Owner #3
Juliette Goglia
Little Girl
Joseph Edward Taylor
Frank
