Johnny Depp
Donnie Brasco / Joseph D. 'Joe' Pistone
Al Pacino
Benjamin 'Lefty' Ruggiero
Michael Madsen
Dominick 'Sonny Black' Napolitano
Bruno Kirby
Nicholas 'Nicky' Santora
Rocco Sisto
Richard 'Richie' Gazzo
Gerry Becker
Agent Dean Blandford FBI
Robert Miano
Alphonse 'Sonny Red' Indelicato
Paul Giamatti
FBI Technician
Gretchen Mol
Sonny's Girlfriend
Tim Blake Nelson
FBI Technician
Terry Serpico
Strip Club Owner
Tony Lip
Philip 'Philly Lucky' Giaccone
Val Avery
Santo Trafficante Jr.
Delanie Fitzpatrick
Daughter
James Bulleit
U.S. Attorney
Keenan Shimizu
Japanese Maitre D'
Rocco Musacchia
Trafficante's Man
Joe Francis
Trafficante's Man
Sal Jenco
Mare Chiaro Bartender
Billy Capucilli
Communion Party Man
Laura Cahill
Communion Party Woman
Doreen Murphy
Mob Girlfriend
Denise Faye
Mob Girlfriend
Elaine del Valle
Mob Girlfriend
Dan Brennan
FBI Photographer
Flint Beverage
Kings Court Cop (uncredited)
Frank Bonsangue
Sonny Red's Crew (uncredited)
Mark Todd Bruner
FBI Agent (uncredited)
Teresa Giudice
Shocked Stripper (uncredited)
Barry Hirschberg
Background (uncredited)
Jim Lavin
Arresting FBI Officer (uncredited)
Peter O'Hara
Passerby (uncredited)
Antone Pagán
Prison Guard for Pacino and Depp (uncredited)
Garry Pastore
Carmine Galante's Bodyguard
Dale Resteghini
Strip Club Patron (uncredited)
Larry Tobias
Man in Bar (uncredited)
Elle Alexander
Mob Girlfriend
Frankie Cee
Civilian (uncredited)
Craig "Radioman" Castaldo